2-Hydroxyglutaric acid diethyl ester

2-Hydroxyglutaric acid diethyl ester - Names and Identifiers

Name	Diethyl2-hydroxyglutarate,2-Hydroxyglutaricaciddiethylester
Synonyms	Diethyl2-hydroxyglutarate Diethyl 2-hydroxypentanedioate 2-Hydroxyglutaric acid diethyl ester Pentanedioic acid, 2-hydroxy-, diethyl ester Pentanedioic acid, 2-hydroxy-, 1,5-diethyl ester Diethyl2-hydroxyglutarate,2-Hydroxyglutaricaciddiethylester
CAS	69134-53-8

2-Hydroxyglutaric acid diethyl ester - Physico-chemical Properties

Molecular Formula	C9H16O5
Molar Mass	204.22
Density	1.1527 g/cm3(Temp: 30 °C)
Boling Point	128-130 °C(Press: 5 Torr)
Solubility	Chloroform (Sparingly), Methanol (Slightly)
Appearance	Oil
Color	Light Brown
pKa	12.84±0.20(Predicted)
Storage Condition	2-8°C

2-Hydroxyglutaric acid diethyl ester - Upstream Downstream Industry

Downstream Products

4-Carbethoxybutyrolactone,γ-Carboethoxy-γ-butyrolactone

2-Hydroxyglutaric acid diethyl ester - Introduction

Diethyl2-hydroxyglutarate,2-Hydroxyglutaric acid (2-hydroxyglutarate) is an organic compound with the chemical formula C10H16O5.

its nature:
-Appearance: colorless liquid
-Melting point:-32 ° C
-Boiling point: 223-224 ° C
-Density: 1.152 g/mL
-Solubility: Soluble in water
-Stability: stable, but avoid contact with strong oxidants and high temperatures.

Its purpose:
- Diethyl2-hydroxyglutarate is used as a potential anti-tumor agent in the field of biomedicine.
-It can also be used as an intermediate in organic synthesis and has application value in some organic synthesis reactions.

Its preparation method:
Diethyl2-hydroxyglutarate can be obtained by reacting diethyl chloroacetate with cyanoacetone in the presence of an alkali catalyst.

Safety Information:
- Diethyl2-hydroxyglutarate, need to store in a cool, dry place, away from fire.
-Oral or inhalation may cause harm to the human body. Avoid inhaling its vapor or direct contact with skin and eyes.
-Wear appropriate personal protective equipment, such as gloves and goggles, during use or handling.
-When handling this compound, follow appropriate safety procedures and pay attention to safety and health measures.
-In the event of a leak or accident, appropriate measures should be taken immediately, including ventilation and the collection of gaseous solvents, to prevent harm to the human body or the environment.
-If ingested or in the eye, seek medical attention immediately and carry the label or container for the compound.

Last Update：2024-04-09 02:00:50